Pengaruh Pemberian Gel Ekstrak Daun Buncis (Phaseolus Vulgaris L.) Sebagai Anti-Inflamasi Penyembuhan Luka Bakar Tikus Putih (Rattus norvegicus) Galur Wistar
Abstract
Keywords
Full Text:
PDFReferences
Alam, G., Singh, M. P., & Singh, A. (2011). Wound healing potential of some medicinal plants. International Journal of Pharmaceutical Sciences: Review and Research, 9, 136–145.
Alba, T. M., Garlet de Pelegrin, C. M., & Sobottka, A. M. (2020). Pharmacognosy ethnobotany, ecology, pharmacology, and chemistry of Anredera cordifolia (Basellaceae): A review. Rodriguésia, 71, e01042019.
http://dx.doi.org/10.1590/2175-7860202071060
Amponsah, I. K., Fleischer, T. C., Annan, K., Dickson, R. A., Mensah, A. Y., & Sarpong, F. M. (2013). Anti-inflammatory, antioxidant and antimicrobial activity of the stem bark extract and fractions of Ficus exasperata Vahl (Moraceae). Journal of Pharmacognosy and Phytochemistry, 2, 38–44.
Anilkumar, M. (2010). Ethnomedicinal plants as anti-inflammatory and analgesic agents. Ethnomedicine, 267–293.
Balafif, R., Andayani, Y., & Gunawan, E. (2013). Analisis senyawa triterpenoid dari hasil fraksinasi ekstrak air buncis (Phaseolus vulgaris Linn) [Tesis S2, Magister Pendidikan IPA, Universitas Mataram].
Batalla, X., Widholm, J. M., Fahey, G. C., Tostado, E., & Lopez, Y. (2006). Chemical components with health implications in wild and cultivated Mexican common bean seeds (Phaseolus vulgaris L.). Journal of Agricultural and Food Chemistry, 54, 2045–2052.
Booy, O., Cornwell, L., Parrott, D., Sutton-Croft, M., & Williams, F. (2017). Impact of biological invasions on infrastructure. In M. Vilà & P. E. Hulme (Eds.), Impact of biological invasions on ecosystem services (pp. 235–247). Cham, Switzerland: Springer.
https://doi.org/10.1007/978-3-319-45121-3
Burnsurvivor. (2014). Anti-inflammatory activity of alkaloids: An update from 2000 to 2015. Molecules, 16(10), 8515–8534.
Chao, P., Lin, S., Lin, K., Liu, Y., Hsu, J., Yang, C., & Lai, J. (2014). Antioxidant activity in extracts of 27 indigenous Taiwanese vegetables. Nutrients, 6, 2115–2130.
Creswell, J. W. (2017). Research design: Qualitative, quantitative, and mixed methods approaches. Thousand Oaks, CA: SAGE Publications.
Corwin, E. J. (2008). Handbook of pathophysiology (3rd ed.). Philadelphia, PA: Lippincott Williams & Wilkins.
Dev, S. K., Choudhury, P. K., Srivastana, R., & Sharma, M. (2019). Antimicrobial, anti-inflammatory and wound healing activity of polyherbal formulation. Biomedicine & Pharmacotherapy, 111, 555–567.
Demilew, W., Adinew, G. M., & Asrade, S. (2018). Evaluation of the wound healing activity of the crude extract of leaves of Acanthus polystachyus Delile (Acanthaceae). Evidence-Based Complementary and Alternative Medicine, 2018, Article ID 2047896.
https://doi.org/10.1155/2018/2047896
Demirci, S., Dogan, A., Demirci, Y., & Sahini, F. (2014). In vitro wound healing activity of methanol extract of Verbascum speciosum. International Journal of Applied Research in Natural Products, 7, 37–44.
Djamil, R. (2012). Antioxidant activity of flavonoid from Anredera cordifolia (Ten) Steenis leaves. International Journal of Pharmacy, 3, 241–243.
Djamil, R., Winarti, W., Zaidan, S., & Abdillah, S. (2017). Antidiabetic activity of flavonoid from binahong leaves (Anredera cordifolia) extract in alloxan induced mice. Journal of Pharmacognosy & Natural Products, 03, 2–5.
Dzomba, P., Togarepi, E., & Mupa, M. (2013). Anthocyanin content and antioxidant activities of common bean species (Phaseolus vulgaris L.) grown in Mashonaland Central, Zimbabwe. African Journal of Agricultural Research.
[Catatan: Tambahkan volume dan nomor halaman jika informasi tersebut tersedia.]
Ebeling, S., Naumann, K., Pollok, S., Wardecki, T., Vidal-Y-SY, S., Nascimento, J. M., Schmidt, G., Brandner, J. M., & Merfort, I. (2014). From a traditional medicinal plant to a rational drug: Understanding the clinically proven wound healing efficacy of birch bark extract. PLOS ONE, 9.
Efendi, F., Citroresksoko, P., & Subagyo, D. (2016). Efektivitas salep ekstrak etanol daun binahong (Anredera cordifolia (Ten.) Steenis) terhadap proses penyembuhan luka gores pada kelinci. Jurnal Farmamedika (Pharmamedica Journal), 1(2), 52–60.
El Sayed, Y. S. (2016). Time course of histomorphologic features during chronic burn wound healing. Damanhour: Damanhour University.
Eming, S. A., Krieg, T., & Davidson, J. M. (2007). Inflammation in wound repair: Molecular and cellular mechanisms. Journal of Investigative Dermatology, 127, 514–525.
Fawole, O. A., Ndhlala, A. R., Amoo, S. O., Finnie, J. F., & Van Staden, J. (2009). Antiinflammatory and phytochemical properties of twelve medicinal plants used for treating gastro intestional ailments in South Africa. Journal of Ethnopharmacology, 123, 237–243.
Frum, Y., & Viljoen, A. M. (2006). In vitro 5 lipoxygenase activity of three indigenous South African aromatic plants used in traditional healing and the stereospecific activity of limonene in the 5 lipoxygenase assay. Journal of Essential Oil Research, 18, 85–88.
Gupta, G. D., & Gand, R. S. (2006). Antiinflammatory activity of tenoxicam gel on carrageenan induced paw oedema in rats. Indian Journal of Pharmaceutical Science, 356–359.
Han, G., & Ceilley, R. (2017). Chronic wound healing: A review of current management and treatments. Advances in Therapy, 34(3), 599–610. https://doi.org/10.1007/s12325-017-0478-y
Jannah, S., Sudarma, S., & Andayani, Y. (2013). Analisis senyawa fitosterol dalam ekstrak buah buncis (Phaseolus vulgaris L.) [Master’s thesis, Universitas Mataram].
Kafkafi, N., Agassi, J., Chesler, E. J., Crabbe, J. C., Crusio, W. E., Eilam, D., Gerlai, R., Golani, I., Gomez Marin, A., Heller, R., Iraqi, F., Jaljuli, I., Karp, N. A., Morgan, H., Nicholson, G., Pfaff, D. W., Richter, S. H., Stark, P. B., Stiedl, O., Stodden, V., Tarantino, L. M., Tucci, V., Valdar, W., Williams, R. W., Würbel, H., & Benjamini, Y. (2018). Reproducibility and replicability of rodent phenotyping in preclinical studies. Neuroscience & Biobehavioral Reviews, 87, 218–232. https://doi.org/10.1016/j.neubiorev.2018.01.003
Kendall, S., Redshaw, S., Ward, S., Wayland, S., & Sullivan, E. (2018). Systematic review of qualitative evaluations of reentry programs addressing problematic drug use and mental health disorders amongst people transitioning from prison to communities. Health and Justice, 6(4).
Kelen, M. E. B., Nouhuys, I. S. V., Kehl, L. C. K., Brack, P., & Silva, D. B. (2015). Plantas alimentícias não convencionais (PANC) no Brasil. UFRGS Ed., Porto Alegre.
Khristantyo, Y., Astuti, I. Y., & Suparman, S. (2011). Profil sifat fisik gel antioksi dan ekstrak buncis (Phaseolus vulgaris L.) dengan basis CMC Na. Pharmacy, 8(1), 125–139.
Kristiningrum, N., & Cahyani, Y. N. (2015). Perbandingan kadar fenol total dan aktivitas antioksidan ekstrak metanol daun kopi robusta dan arabika. Jurnal e Pustaka Kesehatan.
Kurnia, N. (2013). Uji aktivitas antioksidan ekstrak air buah buncis (Phaseolus vulgaris L.) [Master’s thesis, Universitas Mataram].
Lin, H., Kuo, S.-C., Chao, P.-D. L., & Lin, T.-D. (1988). A new sapogenin from Boussingaultia gracilis. Journal of Natural Products, 51, 797–798.
Lima, G. R. M., Montenegro, C. A., Almeida, C. L. F., Athayde Filho, P. F., Barbosa Filho, J. M., & Batista, L. M. (2011). Database survey of anti inflammatory plants in South America: A review. International Journal of Molecular Science, 12(4), 2692–2749.
Laut, M., Ndaong, N. A., & Utami, T. (2019). Cutaneous wound healing activity of herbal ointment containing the leaf extract of Acalypha indica L. on mice. J Phys, 1146(1), 1–6.
Mala, S. N., & Feladita, N. (2022). Uji aktivitas antiinflamasi dalam sediaan salep daun binahong (Anredera cordifolia (Ten.) Steenis) terhadap kelinci jantan (Orytolagus cuniculus). Jurnal Analis Farmasi, 7(1), 57–68.
Miguel, M. G. (2010). Antioxidant and anti inflammatory activities of essential oils: A short review. Molecules, 15, 9252–9287.
Mittal, A., Sardana, S., & Pandey, A. (2013). Herbal boon for wounds. International Journal of Pharmacy and Pharmaceutical Sciences, 5, 1–12.
Mogale, M. M. P., Raimondo, D. C., & VanWyk, B. E. (2019). The ethnobotany of Central Sekhukhuneland, South Africa. South African Journal of Botany, 122, 1–550.
Molan, A.-L., Mohamad Faraj, A., & Saleh Mahdy, A. K. (2012). Antioxidant activity and phenolic content of some medicinal plants traditionally used in northern Iraq. Phytopharmacology, 2(2), 224–233.
Mulia, K., Muhammad, F., & Krisanti, E. (2017). Extraction of vitexin from binahong (Anredera cordifolia (Ten.) Steenis) leaves using betaine–1,4 butanediol natural deep eutectic solvent (NADES). AIP Conference Proceedings, 020018, 1–4.
Nahak, G., Suar, M., & Sahu, R. K. (2013). Antioxidant potential and nutritional values of vegetables: A review. Research Journal of Medicinal Plants.
Nilasari, A. O. (2018). Efektivitas pemberian gel daun kersen (Muntingia calabura) terhadap penyembuhan luka bakar pada tikus putih (Rattus norvegicus) [Thesis, University unspecified].
Nugrahani, R. (2015). Analisis potensi serbuk ekstrak buncis (Phaseolus vulgaris L.) sebagai antioksidan [Master’s thesis, Universitas Mataram].
Okem, A. (2011). Pharmacological activities of selected South African medicinal plants [Master’s thesis, University of KwaZulu Natal, South Africa].
Owen, C. A. (2005). Proteinases and oxidants as targets in the treatment of chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society, 2(4), 373–385. https://doi.org/10.1513/pats.200504-029SR
Pandey, K., Sharma, P. K., & Dudhe, R. (2012). Antioxidant and anti inflammatory activity of ethanolic extract of Parthenium hysterophorus Linn. Asian Journal of Pharmaceutical and Clinical Research, 5, 28–31.
Pariyana, M., Saleh, I., Tjekyan, S., & Hermansyah, H. (2016). Efektivitas pemberian ekstrak daun buncis (Phaseolus vulgaris L.) [Anredera cordifolia] terhadap ketebalan jaringan granulasi dan jarak tepi luka pada penyembuhan luka bakar tikus putih (Rattus norvegicus). Jurnal Kedokteran dan Kesehatan, 3(3), 155–165.
Parsons, M. H., Banks, P. B., Deutsch, M. A., Corrigan, R. F., & Munshi South, J. (2017). Trends in urban rat ecology: A framework to define the prevailing knowledge gaps and incentives for academia, pest management professionals (PMPs), and public health agencies to participate. Journal of Urban Ecology, 3, 1–8. https://doi.org/10.1093/jue/jux005
Pellegrini, M. O. O., & Imig, D. (2019). Basellaceae. In Flora do Brasil 2020 em construção. Instituto de Pesquisas Jardim Botânico do Rio de Janeiro. Retrieved from [URL].
Pitojo, S. (2004). Benih buncis. Kanisius.
Prakash, A. (2021). Antioxidant activity [Report]. Medallion Laboratories Analytical Progress. Surakarta, Indonesia.
Puckett, E. E., Park, J., Combs, M., Blum, M. J., Bryant, J. E., Caccone, A., Costa, F., Deinum, E. E., Esther, A., Himsworth, C. G., Keightley, P. D., Ko, A., Lundkvist, Å., McElhinney, L. M., Morand, S., Robins, J., Russell, J., Strand, T. M., … Munshi South, J. (2016). Global population divergence and admixture of the brown rat (Rattus norvegicus). Proceedings of the Royal Society B: Biological Sciences, 283, 20161762. https://doi.org/10.1098/rspb.2016.1762
Rahmawati, L., Fachriyah, E., & Kusrini, D. (2013). Isolation, identification and test of antioxidant activities of leaves flavonoid compounds (Anredera cordifolia (Ten.) Steenis). Chem Info, 1, 1–10.
Reddy, G. A. K., Priyanka, B., Saranya, C. S., & Kumar, C. A. K. (2012). Wound healing potential of Indian medicinal plants. International Journal of Pharmacy: Review and Research, 2, 75–87.
Rida, W. N., & Taharuddin. (2021). Efektifitas pemberian daun binahong (Anredera cordifolia (Ten.) Steenis) terhadap penyembuhan luka bakar pada tikus: Literature review. Borneo Student Research, 2(2), 1024–1031.
Sabarahi. (2010). Anti-inflammatory, anti oxidant and wound healing properties of selected South African medicinal plants. Desertasi.
Department of Biotechnology and Food Technology, Durban University of Technology, Durban, South Africa.
Sagnia, B., Fedeli, D., Casetti, R., Montesano, C., Falcioni, G., & Colizzi, V. (2014). Antioxidant and anti inflammatory activities of extracts from Cassia alata, Eleusine indica, Eremomastax speciosa, Carica papaya and Polyscias fulva medicinal plants collected in Cameroon. PLoS ONE, 9.
Schweinfurth, M. K. (2020). The social life of Norway rats (Rattus norvegicus). eLife, 9, e54020. https://doi.org/10.7554/eLife.54020
Sharma, Y., Jeyabalan, G., Singh, R., & Semwal, A. (2013). Current aspects of wound healing agents from medicinal plants: A review. Journal of Medicinal Plants Studies, 1, 1–11.
Sihombing, N. C. (2010). Formula gel antioksidan ekstrak buah buncis (Phaseolus vulgaris L.) dengan menggunakan basis AQUPEC 505 HV. Jurnal Ilmiah Universitas Padjadjaran.
Souza, V. C., & Lorenzi, H. (2012). Botânica sistemática: Guia ilustrado para identificação das famílias de fanerógamas nativas e exóticas do Brasil (3ª ed.). Instituto Plantarum.
Sumartiningsih, S. (2011). The effect of Binahong to hematoma. International Journal of Medical and Health Sciences, 5, 244–246.
Susanti, G. (2017). Efek anti inflamasi ekstrak daun buncis topikal terhadap jumlah PMN neutrofil pada tikus jantan Sprague Dawley. Jurnal Kesehatan, 8(3), 351–357.
Thakur, R., Jain, N., Pathak, R., & Singh Sandhu, S. (2011). Practices in wound healing studies of plants. Evidence Based Complementary and Alternative Medicine, 2011, 1–17.
Tsala, D. E., Aamadou, D., & Habtemariam, S. (2013). Natural wound healing and bioactive natural products. Phytopharmacology, 4, 532–560.
Waluyo, N., & Djuariah, D. (2013). Varietas varietas buncis (Phaseolus vulgaris L.) yang telah dilepas oleh Balai Penelitian Tanaman Sayur. Balai Penelitian Tanaman Sayur.
Wassung, K. (2012). The role of inflammation in the healing process. Retrieved from
http://www.planetchiropractga.com/files/2012-02-12/the_role_of_inflammation_in_the_healing_process.ABUTT.pdf
Yang, R. Y., Lin, S., & Kuo, G. (2008). Content and distribution of flavonoids among 91 edible plant species. Asia Pacific Journal of Clinical Nutrition, 17, 275–279.
DOI: https://doi.org/10.51849/j-p3k.v6i2.616
Refbacks
- There are currently no refbacks.







